Senior Research Scientist-Ruan Lab - The Jackson Laboratory - Farmington, CT |
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Senior Research Scientist-Ruan Lab

The Jackson Laboratory | Farmington, CT

The Jackson Laboratory
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Senior Research Scientist

Dr. Yijun Ruan, Principal Investigator



About The Jackson Laboratory for Genomic Medicine: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, JAX-GM is conveniently located midway between NYC and Boston in the heart of Connecticut's growing bioscience industry. Our mission at JAX-GM is to discover the complex causes of disease, develop diagnostics and therapeutics, and ultimately empower the global medical community.


JAX-GM is part of an exciting, internationally-recognized research and educational institution with unparalleled genomic resources and research support services. Seeking to advance personalized medicine, we draw on the institution's distinguished history and on the innovative expertise of our growing faculty, who are recruited from among the world’s top scientific labs and institutions.


About the position: This position will join the The Ruan Lab and requires a scientist with expertise in genomics in general and epigenomics/chromatin biology in specific to support the JAX Center for 3D genome biology. This center is currently funded by two NIH center grants (4DN and ENCODE) and the Roux endowment, and its mission is to develop cutting-age technologies for comprehensive mapping of 3D genome organizations in human and mouse, and to uncover the topological mechanisms that control important genome functional modulation including gene transcription regulation. In this position within the JAX 3D genome center, the incumbent will provide scientific and programmatic leadership in the strategic discussion, technological development, experimental implementation, and data analysis/ interpretation, etc. The role will involve significant interaction and collaboration within the center, The Jackson Laboratory, and with external partners, particularly within the 4DN and ENCODE consortia.  This position offers great growth opportunity to contribute both in novel technology development and advanced genomic discoveries that have immediate relevance in genetics and clinical significance in an innovative and fast-paced team environment.





  • Design and implement large NIH grants and act as co-PI and Program Director (20-30%)
  • Act as co-Investigator on collaborative research grants, internally and as sub-contract (40%)
  • Act as sub-contract PI to outside research grants (20%)
  • Participate in international forums designed to set standard operating procedures for genetic/genomic research (15-20%)





  • PhD or equivalent in molecular biology, genomics, or related discipline with 5+ years of relevant experience in academic institutions or biotech/industry
  • Knowledge and experience in the preparation and execution of successful grant proposals to public or private funding institutions
  • Evidence of scientific productivity demonstrated by publications in high-quality peer-reviewed journals
  • Knowledge and experience in developing and managing successful large scale scientific programs, including management of subcontracts with external investigators, including building an effective and productive research team
  • Experience overseeing the development of relevant research projects by using new technologies, such as DNA sequencing and computational modeling
  • Demonstrated ability to work with people across departments and scientific fields, and to gain their cooperation and commitment to projects with demanding deadlines
  • Excellent written and oral communication skills
  • Excellent organizational skills to track multiple inputs, delegate tasks and track their progress
  • Demonstrated ability to maintain a budget for independent and large scale research awards


APPLICATION INSTRUCTIONS:  Please include a cover letter along with your resume/CV. Applications without cover letters will not be considered. 




The Jackson Laboratory began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.


  • Uncover more of our historic milestones, including the 26 Nobel prizesassociated with our research, resources, and education
  • Read our latest news & insightsfor a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights



The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

Required Skills

Job Code: 6994
Posted On: 2018-02-09 01:33:33
Closing Date: Open Until Filled
Telecommute: No
Categories: Science
Job Type: Regular
Job Status: Full Time
Similar Jobs: Within 25 miles of 06034, Science

Additional Contact Info

Phone: 207 288-6103